Top 100 Medical Startups to Watch in 2026

Top 100 Medical Startups to Watch in 2026

The medical startup scene is seeing major investment across various specializations. Companies are tackling everything from elder care to neurotechnology.

For example, Neuralink has raised $1.3 billion to develop brain-computer interfaces. Meanwhile, newer companies like Aster are addressing specific needs like OB/GYN clinic management.

Below is our list of 100 Medical startups worth keeping an eye on.

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Honor Logo

Honor has built the world’s largest home care network, connecting local agencies and care professionals with families seeking support for aging loved ones. Their technology platform helps modernize agency operations and provides caregivers with tools to deliver high quality in-home care.

HeadquartersConcord, California, United States
Year Founded2014
FoundersCameron Ring, Monica Lo, Sandy Jen, Seth Sternberg
Funding Amount$625M
Startup SizeLarge Team (251-1,000)
Last Funding StatusDebt Financing
Top InvestorsAndreessen Horowitz, Alumni Ventures, 8VC, Slow Ventures, Thrive Capital
OpenEvidence Logo

OpenEvidence builds an AI-powered search engine designed for medical professionals to find clinical answers. The platform provides evidence-based support for treatment decisions by rapidly analyzing medical literature.

HeadquartersCambridge, Massachusetts, United States
Year Founded2021
FoundersDaniel Nadler, Zachary Ziegler
Funding Amount$317M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsSequoia Capital, Coatue, Conviction, Thrive Capital, Kleiner Perkins
Neuralink Logo

Neuralink develops brain-computer interfaces designed to treat neurological disorders. Their technology aims to restore autonomy for people with paralysis by enabling them to control computers and mobile devices directly with their thoughts.

HeadquartersFremont, California, United States
Year Founded2016
FoundersDongjin Seo, Elon Musk, Max Hodak
Funding Amount$1.3B
Startup SizeLarge Team (251-1,000)
Last Funding StatusVenture Round
Top InvestorsValor Equity Partners, Lightspeed Venture Partners, Sequoia Capital, Craft Ventures, Founders Fund
Midi Health Logo

Midi Health runs a virtual clinic delivering expert care for women navigating perimenopause, menopause, and other midlife hormonal changes. Their service connects patients with trained specialists who develop personalized treatment plans to address a wide range of symptoms.

HeadquartersLos Angeles, California, United States
Year Founded2021
FoundersJoanna Strober, Sharon Meers
Funding Amount$152M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsFelicis, GV, Muse Capital, Operator Collective, Emerson Collective
Ambience Healthcare Logo

Ambience Healthcare has built an AI operating system that automates critical workflows for healthcare organizations, from clinical documentation to coding. Their suite of tools helps reduce the administrative burden on clinicians, allowing them to focus more on patient care.

HeadquartersSan Francisco, California, United States
Year Founded2020
FoundersMichael Ng, Nikhil Buduma
Funding Amount$319.3M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsAndreessen Horowitz, Oak HC/FT, Kleiner Perkins, Georgian, Liquid 2 Ventures
Aster Logo

Aster builds an AI-powered operating system specifically for OB/GYN and women’s health practices. The platform is designed to streamline clinic operations, automate clinical documentation, and improve the patient experience.

HeadquartersSan Francisco, California, United States
Year Founded2023
FoundersFifi Kara
Funding Amount$2.4M
Startup SizeFounding Team (1-10)
Last Funding StatusPre-Seed
Top InvestorsOctopus Ventures, Zeal Capital Partners, Everywhere Ventures, Cake Ventures, Cornerstone VC
OrganOx Logo

OrganOx builds a transportable medical device that keeps donor organs warm and functional outside the body. Their technology is designed to extend the time an organ is viable for transplant, improving the quality of the organ and increasing the chances of a successful surgery.

HeadquartersOxford, Oxfordshire, United Kingdom
Year Founded2008
FoundersPeter Friend
Funding Amount$207M
Startup SizeMid-Size Team (51-250)
Last Funding StatusVenture Round
Top InvestorsAmadeus Capital Partners, HealthQuest Capital, Business Growth Fund, Soleus Capital, Intuitive Ventures
MoldCo Logo

MoldCo has built a digital health platform for mold exposure care. Their service connects patients with specialized consultations, at-home testing, and personalized treatment plans.

HeadquartersBoston, Massachusetts, United States
Year Founded2023
FoundersAriana Thacker
Funding Amount$11M
Startup SizeLean Team (11-50)
Last Funding StatusSeed
Top InvestorsSALT, Cantos, Collaborative Fund, Starship Ventures, Boost VC
Thyme Care Logo

Thyme Care created a value-based care model that provides comprehensive navigation and support for cancer patients. They partner with health plans and oncologists to guide individuals through their treatment journey, aiming to improve both the experience and outcomes.

HeadquartersNashville, Tennessee, United States
Year Founded2020
FoundersBobby Green, Robin Shah
Funding Amount$274M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsAndreessen Horowitz, Bessemer Venture Partners, Town Hall Ventures, Foresite Capital, AlleyCorp
Avenzo Therapeutics Logo

Avenzo Therapeutics develops next-generation oncology therapies for patients with cancer. Their team advances a portfolio of promising clinical-stage treatments designed to address significant unmet needs in cancer care.

HeadquartersSan Diego, California, United States
Year Founded2022
FoundersAthena Countouriotis, Mohammad Hirmand
Funding Amount$841.9M
Startup SizeLean Team (11-50)
Last Funding StatusSeries B
Top InvestorsOrbiMed, New Enterprise Associates, INCE Capital, SR One, Lilly Asia Ventures

90 Additional Medical Startups Worth Following

Our top 10 picks offer a glimpse into a much larger movement. Combined, the companies on our full list have raised over $20 billion, tackling big problems in areas like biotech and AI.

You’ll find a mix of newcomers and more established names. Here are the other companies making a mark on the medical industry.



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