Top 100 Health Care Startups to Watch in 2026

Top 100 Health Care Startups to Watch in 2026

The health care industry is being reshaped by startups applying AI and addressing specific needs like aging and mental wellness. Companies are attracting significant investment for these targeted approaches.

For example, Commure has raised over $820.5M for its AI platform, while Odyssey Therapeutics is developing new medicines with $700M in funding. Other areas like aging care are also prominent, with companies like Honor securing $625M to improve home care services.

Below is our list of 100 Health Care startups worth keeping an eye on.

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Oura Logo

Oura creates a smart ring that tracks sleep, activity, and readiness to help users understand their overall health. Their wearable technology provides personalized insights for optimizing daily performance and well being.

HeadquartersOulu, Oulu, Finland
Year Founded2013
FoundersMarkku Koskela, Petteri Lahtela
Funding Amount$598.3M
Startup SizeLarge Team (251-1,000)
Last Funding StatusDebt Financing
Top InvestorsAndreessen Horowitz, Temasek Holdings, Citi, Alumni Ventures, Forerunner
Inspiren Logo

Inspiren builds an AI-powered platform for senior living facilities to monitor patient care and safety. Their technology analyzes clinical workflows and staff-patient interactions to provide insights that improve overall care quality.

HeadquartersBrooklyn, New York, United States
Year Founded2016
FoundersMichael Wang, Paul Coyne, Vincent Cocito
Funding Amount$142.8M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries B
Top InvestorsPrimary Venture Partners, Insight Partners, Scale Venture Partners, Story Ventures, Studio VC
Spring Health Logo

Spring Health provides a comprehensive mental health solution that employers and health plans can offer to their people. The company uses a data-driven approach to guide individuals to the right support, whether it’s therapy, coaching, or medication management.

HeadquartersNew York, New York, United States
Year Founded2016
FoundersAbhishek Chandra, Adam Chekroud, April Koh, Catherine Schwaber
Funding Amount$466.5M
Startup SizeMajor Organization (1,001-5,000)
Last Funding StatusSeries E
Top InvestorsNorthzone, Tiger Global Management, AlleyCorp, Rethink Impact, Operator Partners
Honor Logo

Honor has created a technology platform and a national network of caregivers to provide in-home care for older adults. Their services help families find and manage professional care, allowing seniors to continue living safely at home.

HeadquartersConcord, California, United States
Year Founded2014
FoundersCameron Ring, Monica Lo, Sandy Jen, Seth Sternberg
Funding Amount$625M
Startup SizeLarge Team (251-1,000)
Last Funding StatusDebt Financing
Top InvestorsAndreessen Horowitz, Alumni Ventures, 8VC, Slow Ventures, Thrive Capital
Eight Sleep Logo

Eight Sleep develops a smart sleep system that dynamically adjusts temperature, elevation, and sound. The system uses biometric data to personalize these settings, helping users achieve deeper sleep and better physical recovery.

HeadquartersNew York, New York, United States
Year Founded2014
FoundersAlexandra Zatarain, Andrea Ballarini, Massimo Andreasi Bassi, Matteo Franceschetti
Funding Amount$262.1M
Startup SizeLean Team (11-50)
Last Funding StatusSeries D
Top InvestorsGeneral Catalyst, Gaingels, Khosla Ventures, Valor Equity Partners, 8VC
Odyssey Therapeutics Logo

Odyssey Therapeutics creates precision immunomodulators and oncology medicines for patients with cancer and inflammatory diseases. Their platform combines immunology and oncology expertise to develop novel therapies that target the underlying drivers of disease.

HeadquartersCambridge, Massachusetts, United States
Year Founded2021
FoundersDavid Pompliano, Gary Glick
Funding Amount$700M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries D
Top InvestorsTPG, General Catalyst, OrbiMed, Lightspeed Venture Partners, Catalio Capital Management
Midi Health Logo

Midi Health created a virtual care clinic to support women through menopause and other midlife hormonal changes. The platform provides access to specialized clinicians who offer personalized treatment for a wide range of symptoms.

HeadquartersLos Angeles, California, United States
Year Founded2021
FoundersJoanna Strober, Sharon Meers
Funding Amount$152M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsFelicis, GV, Muse Capital, Operator Collective, Emerson Collective
Ambience Healthcare Logo

Ambience Healthcare builds an AI operating system to help healthcare organizations manage documentation, coding, and complex clinical workflows. Their platform gives clinicians a suite of AI tools to automate administrative duties, freeing them up to focus on patient care.

HeadquartersSan Francisco, California, United States
Year Founded2020
FoundersMichael Ng, Nikhil Buduma
Funding Amount$319.3M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries C
Top InvestorsAndreessen Horowitz, Oak HC/FT, Kleiner Perkins, Georgian, Liquid 2 Ventures
Doctronic Logo

Doctronic created an AI-powered platform that provides secure, instant medical guidance. The service also offers users seamless 24/7 access to licensed physicians for consultations.

HeadquartersNew York, New York, United States
Year Founded2024
FoundersAdam Oskowitz, Matt Pavelle
Funding Amount$25M
Startup SizeMid-Size Team (51-250)
Last Funding StatusSeries A
Top InvestorsLightspeed Venture Partners, Union Square Ventures, MANTIS Venture Capital, Tusk Venture Partners, Seven Stars
Commure Logo

Commure builds a universal platform of composable solutions designed to unite the fragmented health ecosystem. Their tools empower developers and care teams to create connected applications that improve the patient and provider experience.

HeadquartersMountain View, California, United States
Year Founded2017
FoundersDiede van Lamoen, Eugene Kuznetsov, Hemant Taneja
Funding Amount$820.5M
Startup SizeLarge Team (251-1,000)
Last Funding StatusVenture Round
Top InvestorsGeneral Catalyst, Quiet Capital, FJ Labs, Human Capital, Greenoaks

90 Additional Health Care Startups Worth Following

Our top 10 picks offer just a glimpse of the work being done in health care. Many more founders are building companies focused on everything from AI-driven diagnostics to more personal patient support.

Together, these startups have raised over $15 billion, representing a mix of brand-new companies and more established ones. Here’s a look at 90 other startups that are shaping the future of health.



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